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in vivo imaging -2
| Long-time, 4 colors, and 3D in vivo imaging. Mikala Egeblad , Andrew Ewald, Zena Werb. UCSF, Dept of Anatomy Researchers at UCSF developed in vivo imaging system capable of multicolor, 3D imaging at multi-points to observe tumor microenvironment in the same live mouse for long time, by using the CSU. |
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Nuclear EGFP in Foxp3+ Tregs in a tumor within a live MMTVPyMT;ACTB-ECFP;Foxp3EGFP mouse. Play (size :7,674 KB) |
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Membrane EGFP in CD11c+ dendritic-like cells in a tumor within a live MMTVPyMT;ACTB-ECFP;CD11-DTR-EGFP mouse. Play (size :60,212 KB) |
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Example of migration of two myeloid cells at the border of a late carcinoma – a low-migratory, dextran-ingesting cell and a high-migratory, dextran-negative cell. Play (size :65,533 KB) |
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Dynamics of several types of stromal cells in different tumor microenvironment for up to 12 hours to find different behaviors of each stromal cell Green：c-fms-EGFP Blue：ACTB-ECFP Red：10 kDa dextran Play (size :90,019kb) |
