DRUG DISCOVERY

spheroid HUVEC-Hep 0h

Designing Spheroids

3D spheroid/organoid models are becoming the new standard for drug discovery applications because of their physiologically relevant characteristics relative to 2D cultured cells. Nobuhiko Kojima and his group at Yokohama City University, Japan, are developing the technologies of designing different types of spheroids with internal microstructures.

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Novel tissue imaging, profiling and single cell sampling approaches

Learn why the detailed analysis of discrete locations of tissue is an important approach for the biomedical field. From such analysis, you could understand the region-specific interaction between delivered drugs and host biomolecules. A practical example is the research of Professor Melanie Bailey (University of Surrey) and her working group.

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subcellular sampling system- covered with red fabric

Subcellular Sampling System

At the NextGen Omics, Professor Melanie Bailey from the University of Surrey will talk about “Novel tissue imaging, profiling and single cell sampling approaches.” She is a Professorial Research Fellow in the Department of Chemistry at the University of Surrey. She had the exclusive chance to test a Yokogawa prototype for subcellular sampling. In this post, you will learn more details about the upcoming subcellular sampling system.

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organoids

Organoids paving the way

The research team of Prof. Prisca Liberali at the Friedrich Miescher Institute for Biomedical Research (FMI) in Basel explored the potential of organoids for drug screening in a unique image-based screening approach assaying an annotated library of compounds to elucidate tissue regenerative mechanisms in organoids.

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