List of Selected Publications : CV8000, CV7000, CV6000

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[1] N. Beztsinna et al., “Quantitative analysis of receptor-mediated uptake and pro-apoptotic activity of mistletoe lectin-1 by high content imaging,” Sci. Rep., vol. 8, no. 1, p. 2768, Dec. 2018.

[2] C. Boreström et al., “A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell–derived kidney model for drug discovery,” Kidney Int., vol. 94, no. 6, pp. 1099–1110, 2018.

[3] S. T. Durant et al., “The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models,” Sci. Adv., vol. 4, no. 6, p. eaat1719, Jun. 2018.

[4] E. H. Finn et al., “Heterogeneity and Intrinsic Variation in Spatial Genome Organization,” Bioarxiv, 2017.

[5] H. Fuse et al., “Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia,” EBioMedicine, vol. 24, pp. 147–158, 2017.

[6] G. Gut, M. D. Herrmann, and L. Pelkmans, “Multiplexed protein maps link subcellular organization to cellular states,” Science (80-. )., vol. 361, no. 6401, 2018.

[7] K.-J. Jang et al., “Introducing an automated high content confocal imaging approach for Organs-on-Chips,” Lab Chip, vol. 19, no. 3, pp. 410–421, 2019.

[8] L.-S. Kontturi, J. van den Dikkenberg, A. Urtti, W. Hennink, and E. Mastrobattista, “Light-Triggered Cellular Delivery of Oligonucleotides,” Pharmaceutics, vol. 11, no. 2. p. 90, 2019.

[9] L. Marrone et al., “Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy,” Stem Cell Reports, vol. 10, no. 2, pp. 375–389, Feb. 2018.

[10] T. Misteli et al., “Effects of human sex chromosome dosage on spatial chromosome organization,” Mol. Biol. Cell, vol. 29, no. 20, pp. 2458–2469, Aug. 2018.

[11] Y. Miyake et al., “Influenza virus uses transportin 1 for vRNP debundling during cell entry,” Nat. Microbiol., 2019.

[12] L. Pelkmans, R. de Groot, J. Lüthi, H. Lindsay, and R. Holtackers, “Large‐scale image‐based profiling of single‐cell phenotypes in arrayed CRISPR‐Cas9 gene perturbation screens,” Mol. Syst. Biol., vol. 14, no. 1, p. e8064, 2018.

[13] A. K. Rai, J. X. Chen, M. Selbach, and L. Pelkmans, “Kinase-controlled phase transition of membraneless organelles in mitosis,” Nature, vol. 559, no. 7713, pp. 211–216, 2018.

[14] R. Sachdev et al., “Endoplasmic Reticulum Stress Induces Myostatin High Molecular Weight Aggregates and Impairs Mature Myostatin Secretion,” Mol. Neurobiol., vol. 55, no. 11, pp. 8355–8373, 2018.

[15] H. M. Schatzl et al., “Cell-to-cell propagation of infectious cytosolic protein aggregates,” Proc. Natl. Acad. Sci., vol. 110, no. 15, pp. 5951–5956, 2013.

[16] H. Shi et al., “Folate-dactolisib conjugates for targeting tubular cells in polycystic kidneys,” J. Control. Release, vol. 293, pp. 113–125, Jan. 2019.

[17] F. Sun et al., “Mixed micellar system stabilized with saponins for oral delivery of vitamin K,” Colloids Surfaces B Biointerfaces, vol. 170, pp. 521–528, Oct. 2018.

[18] A. C. Tuck et al., “Distinctive features of lincRNA gene expression suggest widespread RNA-independent functions,” Life Sci. Alliance, vol. 1, no. 4, p. e201800124, Aug. 2018.

[19] I. Velter et al., “Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery,” Cell Chem. Biol., vol. 25, no. 5, pp. 611-618.e3, 2018.

[20] A. Verheyen et al., “Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes,” Stem Cell Reports, vol. 11, no. 2, pp. 363–379, Aug. 2018.

[21] L. Vranckx et al., “Molecular mechanism of respiratory syncytial virus fusion inhibitors,” Nat. Chem. Biol., vol. 12, no. 2, pp. 87–93, 2015.

[22] J. Wang et al., “A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins,” Cell, vol. 174, no. 3, pp. 688-699.e16, 2018.

[23] Y. Yu, B. Blokhuis, Y. Derks, S. Kumari, J. Garssen, and F. Redegeld, “Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models,” Oncoimmunology, vol. 7, no. 11, p. e1504729, Nov. 2018.

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