Life Science

Unlocking Life with Precision

Yokogawa’s sensitivity and precision solutions enable rapid and accurate measurements, empowering groundbreaking research, accelerating drug discovery, and optimizing bio-production at scale.

 

Image-Based Solutions​

Image-based solutions for science and pharmaceutical drug development.

Yokogawa’s unique imaging designs and analysis tools improve sensitivity and speed for all your scientific exploration. Our instruments provide high-quality data, for maximized research goals.​

 

Image based assays

Automated Instruments

Automated instruments accelerate research by streamlining routine life science tasks.​

​Yokogawa's automation tackles experimental overload, freeing researchers for more insightful questions and creative exploration. These systems can accelerate drug discovery, time to market, and scientific publication.

Automated instruments

Digital Solutions

Digital solutions to monitor and consolidate complex pharmaceutical manufacturing processes​.

​Yokogawa's robust information sharing tools transcend conventional research organizations. They foster connections that drive problem-solving efficiency and overall experimental effectiveness.​

 

Digital solutions

Details

Image-Based Solutions​

Image-based solutions for science and pharmaceutical drug development. ​

​Yokogawa’s unique imaging designs and analysis tools improve sensitivity and speed for all your scientific exploration. Our instruments provide high-quality data, for maximized research goals.​

Automated Instruments

Automated instruments accelerate research by streamlining routine life science tasks.​

​Yokogawa's automation tackles experimental overload, freeing researchers for more insightful questions and creative exploration. These systems can accelerate drug discovery, time to market, and scientific publication.

Digital Solutions

Digital solutions to monitor and consolidate complex pharmaceutical manufacturing processes​.

​Yokogawa's robust information sharing tools transcend conventional research organizations. They foster connections that drive problem-solving efficiency and overall experimental effectiveness.​

Yokogawa Life Science

We post our information to the following SNSs.
Please follow us.

•Ⅹ (former : Twitter) @Yokogawa_LS
•Facebook Yokogawa Life Science
•LinkedIn Yokogawa Life Science
•YouTube Life Science Yokogawa

 

Yokogawa's Official Social Media Account List

Social Media Account List

Resources

Prehľad:

Visualizing the cell behavioral basis of epithelial morphogenesis and epithelial cancer progression

Prehľad:

Faster, Deeper, and Clearer -in vivo molecular imaging technology-

Prehľad:

Discovering the Basic Principles of Life through the Live Imaging of C. elegans

Prehľad:

Closing in on Neuronal Circuit Dynamics through High-speed, fMCI.

Prehľad:

New Era in Manmmalian Genetics Research: To utilize the same embryo after long-time 3D observation!

Prehľad:

Getting Closer to “Plant Cell World”with High-speed Live Imaging and Image Information Processing.

Prehľad:

Spinning Disk Confocal Microscopy for Quantitative Imaging and Multi-Point Fluorescence Fluctuation Spectroscopy.

Prehľad:

On-site manipulation of protein activities: Understanding intricate cell signaling pathways.

Prehľad:

Use of the spinning disk confocal at the Harvard Medical School microscopy core.

Prehľad:

In recent years, single cell analysis has become increasingly popular due to the new development of advanced and high sensitivity analytical methods.
SS2000 is a revolutionary system that can sample subcellular components and a whole cell by using a glass capillary tip with an inner diameter of a few μm while imaging with a confocal microscope.
This application note provides an example of single cell RNA sequencing scRNA seq) from cells sampled by SS2000, and the data is comparable to conventional methods.

Prehľad:

In recent years, single-cell studies have become increasingly popular as analytical techniques have become more sensitive and widespread.
The SS2000 is a revolutionary device that can sample intracellular components and single cells using glass capillary tips with a diameter of several micrometers while performing confocal microscope imaging. These application notes introduce examples of sampling for various cell types.

Prehľad:

In recent years, research on single cells has become increasingly popular. With more sensitive analytical techniques, it has become possible to analyze specific intracellular components such as organelles, even at the single-cell level.
The SS2000 is an innovative system that can sample subcellular intracellular components using a glass capillary having a tip diameter of only a few micrometers while imaging with a confocal microscope.
In this application note, we introduce a case where after drug treatment, intracellular components were sampled by the SS2000 and analyzed by single-cell mass spectrometry.

Prehľad:

The SS2000 is a revolutionary system that allows both confocal imaging and sampling of targeted intracellular components or single cells using a glass tip with an inner diameter of a few micrometers. The SS2000 includes an incubator as well as highcontent imaging functions, such as long time-lapse observation, machine learning, and label-free analysis.
The SU10 is an innovative device that delivers target substances directly into cells or into nuclei with a nanopipette that has a tip outer diameter as small as a few tens nm.
This application note shows a case study of sampling and analysis with the SS2000 from cells delivered intracellularly with the SU10.

Application Note
Prehľad:

In recent years, single-cell studies have become increasingly popular, leading to the development of instruments capable of spatial omics - the integration of samples' 3D locations and their omics data. The SS2000 is a revolutionary device that can collect intracellular components at the single-cell level and image the samples using a confocal microscope. In this application note we introduce the research performed by Dr. Okada of The University of Tokyo, who established an intra single living cell sequencing (iSC-seq) method which uses SS2000 to sample intracellular components from osteoclasts (a type of multinucleated giant cell) and analyzes them through next-generation sequencing.

Application Note
Application Note
Prehľad:

Comparison between CSU and conventional LSM in 4D movies.

Prehľad:

To investigate interactive dynamics of the intracellular structures and organelles in the stomatal movement through live imaging technique, a CSU system was used to capture 3-dimensional images (XYZN) and time-laps images (XYT) of guard cells.

Application Note
Prehľad:

Long-term observation of mitosis by live-cell microscopy is required for uncovering the role of Cohesin on compartmentalized nuclear architecture which is linked to nuclear functions.
To perform long term observation of mitosis devices are needed that have low phototoxic effects on living cells and enable high speed imaging. By using the CSU W-1 confocal scanner unit for time lapse imaging entrance into mitosis, mitotic progression and exit can be examined.

Application Note
Prehľad:

Cell stage categorized using FucciTime lapse imaging of Fucci-added Hela cells was conducted over 48 hrs at 1 hr intervals. Gating was performed based on the mean intensities of 488 nm and 561 nm for each cell. They were categorized into four stages, and the cell count for each was calculated.

Application Note
Prehľad:

The CV8000 nuclear translocation analysis software enables the analysis of changes in the localization of signal molecules that transfer between cytoplasm and nuclei, such as proteins. The following is an example of the translocation analysis of NFκB, a transcription factor.

Prehľad:

The CQ1 confocal image acquisition mechanism with the distinctive CSU® unit has a function to sequentially acquire fine cell images along the Z-axis and capture information from the entire thickness of
cells which include heterogenic populations of various cell cycle stages. In addition, saved digital images can be useful for precise observation and analysis of spatial distribution of intracellular molecules.
The CQ1 capability to seamlessly analyze images and obtain data for things such as cell population statistics to individual cell morphology will provide benefits for both basic research and drug discovery
targetingM-cell cycle phase.

Application Note
Prehľad:
  • Colony Formation
  • Scratch Wound
  • Cytotoxicity
  • Neurite Outgrowth
  • Co-culture Analysis
  • Cell Tracking
Prehľad:

Faster, Brighter, and More Versatile Confocal Scanner Unit

Application Note
Prehľad:

CV1000 clears the hurdle in Live Cell Imaging
All-in-one Live cell imaging solution

Application Note
Prehľad:

Welcome to The New World of High Content Analysis
High-throughput Cytological Discovery System

Prehľad:

In recent years, research on single cells has become increasingly popular, but with more sensitive analytical techniques, it has become possible to analyze specific intracellular components such as organelles at the single-cell level.

The SS2000 is an innovative system that can sample intracellular components at the single-cell level using a tip (glass capillary) with a diameter of several micrometers while imaging with a confocal microscope. In this application note, we introduce a case in which intracellular components were sampled by SS2000 and genetic analysis was performed by qPCR.

Application Note
Prehľad:

Cell clusters are directly measured with high-throughput 3D imaging Confocal Quantitative Image Cytometer

Application Note
Prehľad:

Wide and Clear
Confocal Scanner Unit

Prehľad:

Fluorescent ubiquitination-based cell cycle indicator (Fucci) is a set of fluorescent probes which enables the visualization of cell cycle progression in living cells.

Yokogawa Technical Report
2.2 MB
Prehľad:

List of Selected Publications : CSU-W1

Prehľad:

List of Selected Publications : CQ1

Prehľad:

List of Selected Publications : CSU-X1

Prehľad:

List of Selected Publications : CV8000, CV7000, CV6000

Prehľad:

This "Tutorial" provides overview of this software, from installation through data analysis.

Prehľad:

In this tutorial, a method for analyzing ramified structure, using CellPathfinder, for the analysis of the vascular endothelial cell angiogenesis function will be explained.

Prehľad:

In this tutorial, a method for analyzing ramified structure, using CellPathfinder, for the analysis of the vascular endothelial cell angiogenesis function will be explained.

Prehľad:

In this tutorial, spheroid diameter and cell (nuclei) count within the spheroid will be analyzed.

Prehľad:

In this tutorial, we will learn how to perform time-lapse analysis of objects with little movement using CellPathfinder, through calcium imaging of iPS cell-derived cardiomyocytes.

Prehľad:

In this tutorial, we will identify the cell cycles G1-phase, G2/M-phase, etc. using the intranuclear DNA content.

Prehľad:

In this tutorial, image analysis of collapsing stress fibers will be performed, and concentration-dependence curves will be drawn for quantitative evaluation.

Prehľad:

In this tutorial, we will observe the change in number and length of neurites due to nerve growth factor (NGF) stimulation in PC12 cells.

Prehľad:

In this tutorial, intranuclear and intracytoplasmic NFκB will be measured and their ratios calculated, and a dose-response curve will be created.

Prehľad:

In this tutorial, we will learn how to perform cell tracking with CellPathfinder through the analysis of test images.

Prehľad:

In this tutorial, using images of zebrafish whose blood vessels are labeled with EGFP, tiling of the images and recognition of blood vessels within an arbitrary region will be explained.

Downloads

Videos

Product Overview
Prehľad:

The Yokogawa business vision states that the company endeavors to achieve Net-zero emissions, ensure the Well-being of all, and make a transition to a Circular Economy by 2050. 

Prehľad:

YOKOGAWA will contribute to technology evolution particularly in measurement and analytical tools to help build a world where researchers will increasingly focus on insightful interpretation of data, and advancing Life Science to benefit humanity.

Prehľad:

YOKOGAWA aspires to establish Smart GMP manufacturing facilities that provide consistent quality and supply while eliminating industrial waste, enhancing productivity and always using high-quality component parts and materials.

Prehľad:

YOKOGAWA creates autonomous operations with high-efficiency automation and optimization that allows growth with minimal deployment of manpower.

Prehľad:

In this webinar, Professor Jonny Sexton discusses a pipeline, developed in the Sexton lab, for the quantitative high-throughput image-based screening of SARS-CoV-2 infection to identify potential antiviral mechanisms and allow selection of appropriate drug combinations to treat COVID-19. This webinar presents evidence that morphological profiling can robustly identify new potential therapeutics against SARS-CoV-2 infection as well as drugs that potentially worsen COVID-19 outcomes.

Správy

Hľadáte viac informácií o našich ľuďoch, technológiách a riešeniach?

Kontaktujte nás

Hore