Latest Advances in Stem Cell-based Disease Modelling and Drug Screening

Yokogawa Life Science at Latest Advances in Stem Cell-based Disease Modelling & Drug Screening Symposium (DASCS)

Yokogawa Life Science is pleased to participate in the DASCS Symposium, a meeting dedicated to the latest advances in stem cell–based disease modelling, organoid technologies, and drug discovery. At our booth, we will showcase live demonstrations of the CellVoyager™ CQ3000, a high‑content imaging system designed to support modern, physiologically relevant cell models and demanding imaging workflows.

As biological research increasingly moves from traditional 2D cultures toward complex 3D systems, stem cell–derived models, and long‑term live‑cell experiments, imaging technologies must evolve accordingly. Researchers today require solutions that combine high spatial and temporal resolution with gentle imaging conditions, reproducibility, and scalability. Yokogawa’s CellVoyager CQ3000 has been developed to meet these needs, enabling scientists to extract meaningful, quantitative data from advanced cellular models without compromising cell health or experimental integrity.

Supporting complex biological models

At the DASCS Symposium, the CQ3000 will be demonstrated with a focus on applications highly relevant to the stem cell and organoid research community. These include imaging of pluripotent and differentiated stem cells, 3D spheroids and organoids, and phenotypic assays used in disease modelling and drug discovery. The system is designed to capture high‑resolution 3D image data while maintaining stable environmental conditions, allowing researchers to observe dynamic cellular processes over extended time periods.
The CQ3000 supports both confocal and widefield imaging modes, enabling flexibility across different assay types. Researchers can visualize fine subcellular structures, monitor morphological changes, and follow functional responses in live cells, while minimizing phototoxicity and photobleaching. This is particularly important for long‑term experiments involving sensitive stem cell populations or complex multicellular structures, where gentle imaging conditions are essential.

Live‑cell imaging and long‑term experiments

One of the key challenges in stem cell and organoid research is maintaining physiological conditions during imaging. The CellVoyager CQ3000 integrates environmental control to support stable temperature, CO₂, and humidity conditions, enabling live‑cell imaging over hours or days. This makes it well suited for studies of differentiation, maturation, and dynamic cellular responses that unfold over time.
During the live demonstrations at the DASCS Symposium, visitors will see how the CQ3000 can be used to capture time‑lapse data and 3D image stacks, providing insights into processes such as cellular organization, growth, and response to external stimuli. These capabilities are particularly valuable for disease modelling workflows, where temporal information and spatial context are critical for understanding complex phenotypes.

From images to quantitative data

High‑content imaging is not only about image acquisition, but also about transforming images into reliable, quantitative data. The CQ3000 is designed to integrate seamlessly with image analysis workflows, supporting multiparametric analysis across large datasets. This allows researchers to move beyond qualitative observations and generate statistically robust results from both 2D and 3D assays.
For applications such as phenotypic screening, target validation, or drug response profiling, this combination of high‑quality imaging and scalable analysis is essential. By enabling consistent data acquisition across plates, conditions, and time points, the CQ3000 supports reproducibility and comparability—key requirements in both academic research and translational drug discovery.

Designed for scalability and collaboration

Many laboratories working with stem cells and organoids face increasing pressure to scale up experiments, whether to compare multiple conditions, analyze patient‑derived models, or support collaborative projects. The CQ3000 is designed to accommodate a wide range of sample formats and experimental designs, making it suitable for both exploratory research and more standardized workflows.
At the DASCS Symposium, Yokogawa’s application specialists will be available to discuss how the CQ3000 can be integrated into existing laboratory environments and adapted to specific research questions. Conversations at the booth will focus on real‑world use cases, experimental challenges, and best practices for imaging complex biological systems.

Meet Yokogawa at DASCS

"Latest advances in stem cell-based disease modelling &drug screening" brings together a vibrant community of scientists working at the forefront of stem cell biology, organoid technology, and disease modelling. Yokogawa Life Science is proud to support this community by providing imaging solutions that enable deeper biological insight and more reliable data.
We invite you to visit our booth to experience live demonstrations of the CellVoyager CQ3000, discuss your current and future imaging needs, and explore how advanced high‑content imaging can support your research. Whether your focus is fundamental stem cell biology, translational disease models, or phenotypic drug screening, our team looks forward to an in‑depth, application‑driven exchange.