OpreX BioPilot is Yokogawa's integrated data platform designed for the life science industry. By seamlessly connecting bioreactors, analyzers, process equipment, Raman Spectroscopy systems, and other data sources, it enables centralized data management, advanced analytics, and workflow automation. This helps improve process reproducibility and reduce product variability throughout the entire bioprocess lifecycle—from process development to manufacturing.
System Integration and Monitoring
- Seamlessly integrate data from bioreactors, analyzers, process equipment, Raman Spectroscopy systems, and other data sources
- Monitor cell culture processes and analyze data in real time through customizable dashboards
- Enable remote monitoring for secure access to process data from virtually anywhere
Process Automation and Operator Support
- Build automation workflows without programming using a no-code workflow designer
- Standardized workflows designed with regulatory compliance and data integrity in mind
- Reduce operator errors through intuitive, guided workflows
- Enhance operational efficiency with operator assistance and incident detection capabilities
Data Management, Analytics, and Control
- Organize and manage collected process data on a batch basis
- Enable predictive process control based on cultivation trend modeling
- Support a seamless transition from process development to manufacturing
- Facilitate technology transfer and scale-up by maintaining consistent data models and workflows across sites and stages of development
Details
OpreX BioPilot Use Cases
System Integration and Monitoring
- Successfully reproduced consistent cell culture performance at both 2 L and 20 L scales by continuously measuring glucose concentration with a Raman sensor and automatically maintaining the target glucose level
- Successfully automated the control of multiple pumps used in perfusion culture, maintaining a constant working volume while regulating glucose concentration
Operator Support and Process Automation
- Automate routine operations through an intuitive user interface by No-code drag and drop function
- Reduce human error by providing step-by-step operator guidance tailored to each customer's cultivation workflow
Data Management and Analytics
- Connect bioreactors, Raman sensors, and offline analyzers to OpreX BioPilot to automatically collect and consolidate data into a single trend view, simplifying process monitoring and data management
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