Intracellular delivery of reagents with low membrane permeability and Live cell time-lapse imaging

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Overview

The SU10 is able to directly deliver substances of interest into single cell (nucleus or cytoplasm), using a “nano” pipette with a tip  outer diameter of only a few tens of nanometers. This allows fluorescent labeling of live cells and live cell imaging immediately after delivery of the substance, which is not possible with conventional methods. In this application note, we will demonstrate the use of the SU10 for introducing a fluorescent reagent into a cell with low membrane permeability and monitor the intracellular dynamics with the CSU-W1 confocal scanner unit.

For further information, download the application note at the top of the page.

Single Cellome Application Note

 

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