The CV8000 features a cell incubator with an improved airtight design that facilitates the observation of cell behavior over long periods of time. In addition, the CV8000 comes with CellPathfinder, a new program that can analyze images of unlabeled cells and 3D images of samples. With these features, the CV8000 improves the efficiency of drug discovery research and biomedical research on leading-edge subjects such as iPS and ES cells.
・Dual spinning disc confocal unit
・Live cell imaging and kinetic assays
・Reliable and validated technology
・High contents analysis system
25/50 μm pinhole disk exchanger※2.
*1 As of September 2017
Fast kinetic responses can be visualized by applying drugs during time lapse recordings.
Ionomycin was applied to A10 cells labeled with Fluo-4 during recording with 100ms intervals.
※1 Depends on conditions and samples.
※1 1 field/well, 4-camea simultaneous recording
Software learns the features of the sampleobjects collected by users.
DPC※1 function is a powerful tool to analyze unstained bright field samples.
※1 Digital phase contrast
|Sample format||Multiple well plate (6, 12, 24, 48, 96, 384, 1536 wells), glass slide|
|Image mode||Confocal mode
max. 4 color simultaneous recording,
Brightfield mode, Phase-contrast
(10x, 20x for 6, 12, 24 well plates)
digital phase contrast (10x 20x)
|Output data format||Image data: 16bit TIFF, PNG
Numerical data: CSV, Original format
|Excitation wavelength||405/445/488/561/640nm, all solid laser, max. 5 lasers
|White light illumination||LED|
|Autofocus||Laser-based mode, Image-based mode|
|Objective lens||Max. 6 lenses are available : Automatically switchable
Dry： 2x, 4x, 10x, 20x, 40x
Water immersion： 40x, 60x
Long working distance： 20x
Phase-contrast： 10x, 20x
|Confocal unit||Microlens-enhanced wide-view dual Nipkow disk confocal scanner, 50 μm pinhole
【Option】 25/50 μm pinhole disk exchanger
|Camera||sCMOS (effective pixels: 2000X2000 pixel size: 6.5 μm), max. 4 cameras|
|Stage incubator||Temperature: 35-40℃ CO2 supply box (CO2: 5%, forced humidification)|
|Dispenser||【Option】Disposable tip type
(For 96 tip , 384 tip type)
|Bar-code reader||【Option】1 or 2 dimension|
|Workstation||Dual-monitor workstation for system control
Dual-monitor workstation for data analysis
|Granularity, Neurite, Nuclear morphology, Nuclear translocation, Plasma membrane translocation, Machine learning, Label-free analysis, 3D analysis, Texture analysis, etc.|
|Operating environment||15-30ºC, 20-70%RH (No condensation）|
|Power supply||Measurement unit: Single-phase 200VAC, 2KVAmax
Workstation for system control : 100VAC, 1.3KVAmax, Workstation for data analysis: 100VAC, 690VAmax
|External dimension||Measurement unit: 1280W×895D×1450H mm|
|Weight||Measurement unit: 510Kg|
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