Data Interpretation and Relevant Models for Drug Screening
Image-based phenotypic screening relies on the extraction of multivariate information from cells cultured in a large number of screened conditions. In this webinar, we explored the application of complex and biologically relevant model systems for drug screening, such as small intestinal organoids.
Key topics include:
- Learn how to upscale, streamline, and automate intestinal organoid handling
- Learn how to image in complex three-dimensional (3D) model systems and how to approach large imaging datasets
- Understand the basics of multivariate analysis on image-inferred features
Speaker
IIya Lukonin, PhD
Scientist, Organoid Phenotyping at Roche IHB, Roche IHB
As Group Lead, interim, and Senior Scientist, Ilya works on establishing phenotypic screening assays in organoid systems. He combines cell culture and assay automation, high-content imaging, and data analysis. Ilya aims to develop robust and high-throughput organoid screening assays and computational tools for data-driven characterisation of various organoid models to increase the speed and reliability of scientific discovery.
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