Single-Cell Analysis Solutions Single Cellome™

Nano-point Delivery

Single Cellome Unit SU10은 현미경으로 표적 세포의 핵과 세포질 내로 선택적인 전달을 가능하게 합니다.
수십 나노미터 직경의 유리 피펫(나노피펫) 팁을 사용하여 세포 손상을 최소화합니다.
Single Cellome Unit SU10은 세포 표면 감지, 천공(puncture), 주입 작업을 자동화하여 다양한 물질을 빠른 속도와 높은 효율로 전달할 수 있습니다.

SU10

 

Subcellular Sampling

Single Cellome System SS2000은 공초점 현미경으로 intracellular components과 전체 세포를 자동으로 샘플링 할 수 있습니다.
배양 중인 세포를 분리할 필요가 없기 때문에 위치 및 형태학적 정보(morphological information)를 유지하면서 샘플링이 가능합니다.
이 샘플링 시스템은 고속, 고해상도 이미지 수집 및 이미지 분석과 같은 고용량 분석(HCA) 기능을 결합합니다.

SS2000

 

  • Nano-point Delivery / Nano-point Sampling SU10

    이 시스템은 나노피펫(nanopipette)을 구성 요소로 사용하여 single cells 의 침투(penetration) 및 주입(injection)을 자동화합니다. 침입성(invasiveness)이 낮은 live single cells에도 조작할 수 있습니다. 이 시스템은 여러 제조업체의 광학 현미경과 통합됩니다.

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  • Subcellular Sampling System SS2000

    SS2000은 배양 중인 세포를 공초점 현미경으로 이미징하면서 단일 세포 수준에서 세포의 특정 영역 또는 세포 전체 영역을 자동으로 샘플링하는 시스템입니다. 이는 배양 중인 세포를 분리할 필요가 없기 때문에 셀의 위치 정보 및 형태학적(morphological) 정보를 유지시킬 수 있습니다.

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자료실

Overview:

In recent years, single-cell studies have become increasingly popular as analytical techniques have become more sensitive and widespread.
The SS2000 is a revolutionary device that can sample intracellular components and single cells using glass capillary tips with a diameter of several micrometers while performing confocal microscope imaging. These application notes introduce examples of sampling for various cell types.

Overview:

In recent years, research on single cells has become increasingly popular, but with more sensitive analytical techniques, it has become possible to analyze specific intracellular components such as organelles at the single-cell level.

The SS2000 is an innovative system that can sample intracellular components at the single-cell level using a tip (glass capillary) with a diameter of several micrometers while imaging with a confocal microscope. In this application note, we introduce a case in which intracellular components were sampled by SS2000 and genetic analysis was performed by qPCR.

Overview:

In recent years, single cell analysis has become increasingly popular due to the new development of advanced and high sensitivity analytical methods.
SS2000 is a revolutionary system that can sample subcellular components and a whole cell by using a glass capillary tip with an inner diameter of a few μm while imaging with a confocal microscope.
This application note provides an example of single cell RNA sequencing scRNA seq) from cells sampled by SS2000, and the data is comparable to conventional methods.

Overview:

SU10 is a novel technology that enables the delivery of target substances directly into cells (nucleus or cytoplasm) using a "nano" pipette made of a glass capillary with an outer tip diameter of tens of nanometers.

Overview:

In recent years, research on single cells has become increasingly popular. With more sensitive analytical techniques, it has become possible to analyze specific intracellular components such as organelles, even at the single-cell level.
The SS2000 is an innovative system that can sample subcellular intracellular components using a glass capillary having a tip diameter of only a few micrometers while imaging with a confocal microscope.
In this application note, we introduce a case where after drug treatment, intracellular components were sampled by the SS2000 and analyzed by single-cell mass spectrometry.

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Overview:

YOKOGAWA will contribute to technology evolution particularly in measurement and analytical tools to help build a world where researchers will increasingly focus on insightful interpretation of data, and advancing Life Science to benefit humanity.

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