Overview
In recent years, research on single cells has been actively conducted. However, with more sensitive analytical techniques, it is now possible to analyze specific intracellular components at the single-cell level.
The SS2000 is an innovative instrument that can collect intracellular components at the single-cell level by using a glass tip with a tip diameter of a few micrometers while imaging with a confocal microscope. This application note showcases an experiment in which the SS2000 was used to collect intracellular components from drugtreated cells and, subsequently, LC/MS was used to detect and quantify drugs in the samples collected.
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The SS2000 is a dual microlens spinning disk confocal microscope for live-cell, high-content imaging which can sample adherent single cells and subcellular material while ensuring the preservation of spatial, morphological, and temporal information.
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