TECH TALK: Cancer Modeling & High-Content Imaging using 3D Cell-Based Assays

Presenters:

Katya Nikolov, MD (Protein Fluidics, Inc.)

Senior Application Scientist

Dan Collins (Yokogawa Electric Corporation)

Field Applications Scientist – Life Science

Abstract

Physiologically relevant 3D cell models are being adopted for disease modeling, drug discovery, and preclinical research due to their functional and architectural similarity to their tissue/sample of origin, especially for oncology research. Multifunctional profiling and assays using 3D cell models such as tumoroids tend to be manual and tedious. Further, high-content imaging of biomarkers in 3D cell models can be difficult.

This two-part webinar presents to you streamlined technologies that can bring consistent timesaving, ease-of-use, and high-quality data to your 3D cell-based workflows:

(A)  The Pu·MA System is a microfluidics-based benchtop automated device for performing “hands-off” 3D cell-based assays. In this webinar, application scientist Dr. Katya Nikolov will present data from optimized assays using tumoroids followed by Yokogawa’s high-content imaging systems for biomarker detection.

(B) Yokogawa’s high-content imaging systems such as CellVoyager CQ1 provide superior confocal imaging using the Nipkow Spinning Disk Confocal Technology. Here, application scientist, Dan Collins will present details of the high-content imaging capabilities, easy-to-use and intuitive image acquisition software, especially for increasing productivity and a streamlined workflow.

Learn How:

• The open platform, Pu·MA System can be used to automate your 3D cell-based assays
• To perform automated IF staining for biomarkers using tumoroid models without perturbing your precious samples
• Image acquisition from 3D cell models using Yokogawa’s high-content imaging platforms
• Image analysis from cells, complex spheroids, colonies, or tissues using the CellPathfinder high content analysis software